The Effect of BI 187004 on the Pharmacokinetics of Cytochrome P450 Substrates (Caffeine, Warfarin, Omeprazole, Metoprolol and Midazolam) and a P Glycoprotein Substrate (Digoxin)
PHASE1
To assess the influence of BI 187004 on kinetics of cytochrome P450 (CYP) a...
Status
Completed
Location
1307.19.1 Boehringer Ingelheim Investigational Site
Relative Bioavailability of Multiple Oral Doses of BI 187004 and Metformin After Co-administration Compared to Multiple Oral Doses of BI 187004 Alone and Metformin Alone in Healthy Male Subjects
PHASE1
To investigate bioavailability of BI 187004 and of metformin after concomit...
Status
Completed
Location
1307.7.1 Boehringer Ingelheim Investigational Site
Relative Bioavailability of a BI 187004 Tablet Formulation in Comparison With an Oral Solution and the Influence of Food on the Tablet Formulation in Healthy Volunteers
PHASE1
To determine the relative bioavailability of an BI 187004 tablet formulatio...
Status
Completed
Location
1307.3.1 Boehringer Ingelheim Investigational Site
Safety and Tolerability, Efficacy, Pharmacokinetic and Pharmacodynamic Study of Three Doses of BI 187004 Over 28 Days in Patients With Type 2 Diabetes Mellitus With and Without Metformin
PHASE2
Assess the safety and tolerability of once daily oral doses of BI 187004 in...
Status
Completed
Location
1307.4.49003 Boehringer Ingelheim Investigational Site